Oreochromis niloticus ve Cyprinus carpio’da Bakır ve Kurşun Etkisinde Kan Serum İyon Düzeyleri

Hikmet Yeter Cogun, Ferit Kargin

Ekoloji, 2013, Issue 87, Pages: 51-57

DOI: https://doi.org/10.5053/ekoloji.2013.877


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In this study, the effects of concentration and exposure time of Cu and Pb on plasma levels of Na+, K+, Ca++, Mg+ and C-l of Cyprinus carpio and Oreochromis niloticus were tested at varying concentrations of metal in the medium and over different periods of time. Fish were exposed to 0.1, 0.5 and 1.0 mg/L Cu and Pb over periods of 10 and 20 days and ion distributions of copper and lead were determined using spectrophotometric method. Plasma ion (Na+, K+, Ca++, Mg and Cl-) levels effected by Pb and Cu. In both species, blood serum Na+ levels decreased after periods tested at exposure to copper while increasing at exposure lead. O. niloticus blood serum K+ levels increased with effect of Cu and Pb concentrations. In
C. carpio Cu concentrations blood serum K+ levels increased while decreased with effect of Pb concentrations after 10 and 20 days of exposure. Ionize Ca++ levels of blood serum in O. niloticus decreased at high concentrations of Cu and in all the concentrations of Pb. In C. carpio blood serums ıonize Ca++ levels decreased at exposure to copper while increasing at exposure to lead after periods tested. In all the concentration of Cu and Pb and periods tested, blood serum Mg+ levels decreased in O. niloticus but an increase was observed in C. carpio. In both species, blood serum Cl- levels while increasing at copper exposure; it was seen that decreasing at lead exposure.


Blood, Cyprinus carpio, ion, Oreochromis niloticus


  • Arellano JM, Storch V, Sarasquete C (1999) Histological Changes and Copper Accumulation in Liver and Gills of the Senegales Sole, Solea senegalensis. Ecotoxicology and Environmental Safety 44: 62-72.
  • Bjerregaard P, Vislie T (1986) Effect of Copper on Ion-And Osmoregulation in the Shore Crab Carcinus maenas Marine Biology 91: 69-76.
  • Bricknell IR, Bowden TJ, Bruno DW, Maclachlan P, Johntone R, Ellis AE (1999) Susceptibility of Atlantic Halibut, Hippoglossus hippoplossus (L.) to Infection with Typical and Atypical Aeromonas salmonicida. Aquaculture 175: 1-13
  • Campana O, Sarasquete C, Blasco J (2003) Effect of Lead on ALA-D Activity, Metallothionein Levels, and Lipid Peroxidation in Blood, Kidney, and Liver of the Toadfish Halobatrachus didactylus. Ecotoxicology and Environmental Safety 55: 116-125.
  • Cerqueira CCC, Fernandes MN (2002) Gill Tissue Recovery After Copper Exposure and Blood Parameter Responses in the Tropical Fish Prochilodus scrofa. Ecotoxicology and Environmental Safety 52: 83-91.
  • Flik G, Verbost PM (1993) Ca2+ and Mg2+ Transport in Gills and Gut of Tilapia Oreochromis mossambicus: A Review. Journal of Experimental Zoology 265: 356-365.
  • Hawkins AD (1981) Aquarium Systems. Academic Pres, London.
  • Heath AG (1987) Water Pollution and Fish Physiology. CRC Press, Florida.
  • Hongstrand C, Ferguson EA, Galves F, Shaw JR, Webb NA, Wood CM J (1999) Physiology of Acute Silver Toxicity in the Starry Flounder (Platichtys stellatus) in Seawater. Journal of Comparative Physiology B 169: 461- 473.
  • Johnson I (1988) The Effects of Combinations of Heavy Metals, Hypoxia and Salinity on Ion Regulation in Crangon crangon (L) and Calcinus maenas (L). Comparative Biochemistry and Physiology 91C (2): 459-463.
  • Lacrox GL, Gordon DJ, Johnstan DJ (1985) Effectsof Low Environmental pH on the Survival, Growth, and
  • Ionic Composition of Postemergent Atlantic Salmon (Salmo salar). Canadian Journal of Fisheries and Aquatic Sciences 42: 768-775.
  • Lauren DJ, Mcdonald DG (1985) Effects of Copper on Branchial Ionoregulation in the Rainbow Trout, Salmo gairdnerii Richardson Modulation by Hardness and pH. Comparative Biochemistry and Physiology Part B 155: 635-644.
  • Linde AR, Sanchez-Galan S, Klein D, Garcıa-Vazquez E, Summer KH (1999) Metallthionein and Heavy Metals in Brown Trout (Salmo trutta) and European Eel (Anguilla anguilla): A Comparative Study. Neotoxicology and Environmental Safety 44: 168-173.
  • Mcgeer JC, Szebedinszky C, Mcdonald DG, Wood CM (2000) Effect of Chronic Sublethal Exposure to Waterborne Cu, Cd or Zn in Rainbow trout 2: Tissue Spesific Metal Accumulation. Aquatic Toxicology 50: 245-256.
  • Morgan IJ, Henry RP, Wood CM (1997) The Mechanism of Acute Silver Nitrate Toxicity in Freshwater Rainbow Trout (Oncorhnchus mykiss) is Inhibition of Gill Na+ and Cl- Transport. Aquatic Toxicology 38: 145- 163.
  • Nussey G, Van Vuren JHJ, Du Preez HH (1995) Effect of Copper on the Haematology and Osmoregulation of the Mozambique tilapia, Oreochromis mossambicus (Cichlidae). Comparative Biochemistry and Physiology 111C: 369-380.
  • Pelgrom SMGJ, Lock RAC, Balm PHM, Wendelaar Bonga SE (1995) Integrated Physiological Response of Tilapia, Oreochromis mossambicus, to Sublethal Copper Exposure. Aquatic Toxicology 32: 303-320.
  • Pratap HB, Fu H, Lock RAC and Wendelaar Bonga SE (1989) Effect of Waterborne and Dietary Cadmium on Plasma Ions of Teleost Oreochromis mossambicus in Relation to Water Calcium Levels. Archives of Environmental Contamination and Toxicology 18: 568-575.
  • Roger JT, Richards JG, Wood CM (2003) Ionoregulatory Disruption as the Toxic Mechanism for Lead in the Rainbow Trout (Oncorhnchus mykiss). Aquatic Toxicology. 64(2): 215-34.
  • Satyavathi C, Rao YP (2000) Inhibition of Na+, K+-ATPase in Penaeus indicus Postlarvae by Lead. Comparative Biochemistry and Physiology Part C 127: 11-22.
  • Sloman KA, Morgan TP, Mcdonald DG, Wood CM (2003) Socially-induced Changes in Sodium Regulation Affect the Uptake of Water-borne Copper and Silver in the Rainbow trouth, Onccorhnchus mykiss. Comparative Biochemistry and Physiology Part C 135: 393-403.
  • Stouthart AJHX, Spanings FAT, Lock RAC, Wendelaar Bonga SE (1995) Effects of Water pH Toxicity to Early Life Stages of Common Carp (Cyprinus carpio). Aquatic Toxicology 32: 31-42.
  • Suresh A, Sivaramakrishna B, Radhakrishnaıah K (1995) Cadmium Induced Changes in Ion Levels and ATPase Activities in the Muscle of the Fry and Fingerlings of the Freshwater Fish, Cyprinus carpio. Chemosphere 30(2): 365-375.
  • Thaker J, Chhaya J, Nuzhat S, Mittal R, Mansuri AP, Kundu R (1996) Effects of Chromium (VI) on Some Ion-Dependent ATPases in Gills, Kidney and Intestine of a Coastal Teleost Periophtalmus dipes. Toxicology 112: 237-244.
  • Viarengo A (1985) Biochemical Effects of Trace Metals. Marine Pollution Bulletion 16(4): 153-158.
  • Wang T, Knudsen PK, Brauner CJ, Busk M, Vıjayan MM., Jensen FB (1998) Copper Exposure Impairs Intra-and Extracelluler Acid-Base Regulation During Hypercapnia in the Fresh Water Rainbow Trout (Oncorhynchus mykiss). Comparative Biochemistry and Physiology B 168: 591-599.
  • Wood CM, Hogstrand C, Galves F, Munger RS (1996) The Physiology of Waterborne Silver Toxicity in
  • Freshwater Rainbow Trout (Oncorhynchus mykiss) 2. The Effects of Silver Thiosulfate. Aquatic Toxicology 35: 111-125.